TRABALHOS PUBLICADOS
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Lateral esophagostomy: An alternative in the initial management of long gap esophageal atresia without fistula
António Sérgio Aloisi, Segirson de Freitas Jr, António César Colombo, Rogério Amalfi, Lourenço Sbragia-Neto, Joaquim M. Bustorff-Silva
Abstract
The authors report an alternative method of cervical esophagostomy that was used in a child with type A esophageal atresia. This method involved performing a lateral esophagostomy in the proximal pouch, preserving its distal end, allowing the child to swallow normally, without choking, while stimulating the spontaneous growth of the proximal esophagus. As a result, the infant could be discharged home on G-tube feedings while waiting for spontaneous growth of the proximal pouch to occur. There were no episodes of aspiration during this period, and definitive reconstruction through end-to-end esophageal anastomosis was accomplished successfully at the age of 18 months. The authors consider that this alternative might increase the possibility of a definitive correction through delayed primary anastomosis of the infant's own esophagus in children with this type of malformation. J Pediatr Surg 35:1827-1829. Copyright © 2000 by W.B. Saunders Company.
Keywords: Esophageal atresia, cervical esophagostomy
2.
Hepatogastroenterology. 2003 Jan-Feb;50(49):146-50.
Retinyl-palmitate reduces liver fibrosis induced by biliary obstruction in rats.
de Freitas Junior S, Bustorff-Silva JM, Castro e Silva Junior O, Jorge Gde L, Leonardi LS.
Department of Surgery, Faculty of Medical Sciences, State University of Campinas UNICAMP, Campinas, Brazil.
Abstract
BACKGROUND/AIMS: The administration of retinoid in various experimental models of induced hepatic cirrhosis has shown antifibrogenic effects. The purpose of this study was to verify if vitamin A could interfere in hepatic fibrosis induced by biliary obstruction.
METHODOLOGY: Male Wistar rats that underwent biliary obstruction were treated 2 weeks before the surgery with a dose of 50 x 10(3) IU retinyl-palmitate, twice a week, and then given the dosage for 5 weeks following surgery. They were then sacrificed and hepatic fragments removed to find out the biochemical dosage of hydroxyproline and the stereologic volume of collagen. Blood samples were also collected to find the biochemical dosage.
RESULTS: The rats that underwent biliary obstruction and received vitamin A presented lower levels of hepatic hydroxyproline (p < 0.001) as well as a lower percentage of collagen tissue than the untreated control rats, but they presented higher AST and ALT serum levels (p < 0.05, p < 0.05).
CONCLUSIONS: Under the above experimental conditions, the administration of vitamin A significantly reduced hepatic fibrosis.
3.
Capítulo 3: A IMPORTÂNCIA DA INVESTIGAÇÃO E DO SEGUIMENTO UROLÓGICOS
Segirson de Freitas Junior; Márcio Lopes Miranda
in: MIELOMENINGOCELE: o dia a dia, a visão dos especialistas, o que devemos esperar do futuro.(Livro)
Organizadores: Valéria Rueda Spers, Daniela Garbellini, Eliane de Assis Souza Penachim
2011, Editora Unigráfica Gráfica e Editora Ltda, São Paulo